This idiom or expression like sentence means:

Talk to me.
Let’s get started.
What’s on your mind?
What are you saying?
Stop wasting my time.
What is the real problem?
What is really bothering you?
Let’s talk about the thing you want to talk about.

Also see:
Cut to the chase.
Beat around the bush.

This idiom or expression like question means:

Speak up.
What do you think?
What are you trying to say?